Maspin as a Tumour Suppressor in Salivary Gland Tumour
Published: December 1, 2014 | DOI: https://doi.org/10.7860/JCDR/2014/.5241
Bassel Tarakji, Nipun Ashok,Mohammad Kinan Sheirawan, Mohammed Alsakran Altamtamimi, Faris Alenzi, Saleh Nasser Azzeghaiby, Kusai Baroudi, Mohammad Zakaria Nassani
1. Faculty, Department of Oral Maxillofacial sciences, Al-Farabi College of Dentistry and Nursing, Riyadh.
2. Faculty, Department of Oral Maxillofacial Sciences, Al-Farabi College of Dentistry and Nursing, Riyadh.
3. Faculty, Department of Restorative Dental Sciences, Al-Farabi College of Dentistry and Nursing, Riyadh.
4. Faculty, Department of Restorative Dental Sciences, Al-Farabi College of Dentistry and Nursing, Riyadh.
5. Faculty, College of Applied Medical Sciences, Salman bin Abdulaziz University, Al-Kharj, Saudia Arabia.
6. Director, Alfarabi College of Dentistry, Kingdom of Saudi Arabia, Riyadh.
7. Faculty, Department of Restorative Dental Sciences, Al-Farabi College of Dentistry and Nursing, Riyadh.
8. Faculty, Department of Restorative Dental Sciences, Al-Farabi College of Dentistry and Nursing, Riyadh.
Correspondence
Dr. Bassel Tarakji,
Faculty, Department of Oral Maxillofacial Sciences, Al-Farabi College of Dentistry and Nursing-P.O Box 85184, Riyadh.
Phone : 00966504623330, E-mail : denpol@yahoo.co.uk
Maspin is a protein that belongs to serin protease inhibitor (serpin) superfamily. The purpose of this study was to review the literature concerning the expression of maspin in salivary gland tumours. A literature search was done using MEDLINE, accessed via the National Library of Medicine PubMed interface. Statistical analysis was not done because only seven studies were available in literature, the collected data were different and the results could not be compared. Expression of maspin was down regulated in more aggressive salivary gland tumours. Maspin may function as a tumour suppressor in salivary gland tumours.
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